When to Opt for IVF?
Infertility can be due to many reasons and IVF should not be considered initially for treatment. It is practised only when other methods like fertility drugs, surgery and artificial insemination have failed. In cases of infertility, the option of IVF is advisable if any one of the partner is diagnosed with any of the following:
o Low sperm counts
o Problems with the uterus or low Fallopian tubes
o Problems with ovulation
o Antibody problems
o Sperms are unable to go inside or survive in the cervical mucus
o An unexplained fertility problem
Raipur Fertility Research Centre is helping people build families successfully for the last 15 years. At IVF Raipur With a high pregnancy rate, it has got excellent ratings by our patients. We have an extremely qualified and committed team of doctors, nurses, embryologists and counselors who work together to strive for excellence in fertility care. The flexible financial options and a long record of success make it one of the best treatment centre for IVF.
Raipur Fertility Centre understands the emotional aspect associated with infertility. Our USP is that We believe in treating patients emotionally as well as physically. We have a holistic approach in our treatment to fertility which can be seen in all the stages of IVF that a patient undergoes.
Stages of IVF Treatment
The following are the stages in every cycle of IVF treatment.
In this process the ovaries are stimulated so that they ripen and are able to release many eggs in one cycle. This is important process where close monitoring is done and fertility drugs are used which helps the patients to maximize their chances of conception. The following are the steps for understanding ovulation induction:
o A Natural Cycle
o A Stimulated Cycle
o Potential Side Effects
o Cycle Cancellation
A Natural Cycle : At the beginning of a menstrual cycle, the pituitary gland releases follicle stimulating hormone (FSH) into the body. This causes immature eggs to develop and eggs within to ripen. Once an egg is mature, a hormone known as lutenizing hormone (LH) is released. This leads the egg to break out and start its journey. It moves to the uterus through the Fallopian tube.
It is seen that usually most women would release one egg in one cycle. There have been instances of some women who release two eggs. Also there are women who have problems and don’t release any egg.
A Stimulated Cycle : During ovulation induction, fertility drugs are administered to mimic the hormones normally released by the body. One week before menstruation which is the beginning of a new cycle, medicines are given so that early ovulation can be avoided. Fertility drugs are given to mature the eggs post the start of the new cycle. During this time, the patient’s cycle will be closely monitored to ensure the desired process is taking place. This also helps in understanding when the eggs mature at which time the fertility drugs are stopped and an injection is given to trigger ovulation.
Benefits: Ovulation Induction is a key step in the in vitro fertilization process. The ability to pin point ovulation helps in retrieving eggs when they are fully mature but before they have been released from the ovaries. The administration of fertility drugs leads to the maturation of multiple eggs at one time which increases the chances of successful conception. When the eggs are collected and fertilized, any extra embryos can be frozen which allows multiple cycles of IVF to be performed without repeating the ovulation induction process each time.
Potential Side Effects: There is always a risk of multiple pregnancies for anyone who undergoes ovulation induction as multiple eggs are likely to be released. Some women may also experience some side effects due to usage of fertility drugs.
Cycle Cancellation: IVF cycle needs to be cancelled if it is seen that patients are not responding too well to the fertility drugs and not developing enough follicles which are required for a successful fertilization. It is also advisable to go for cancellation when there is a risk of ovarian hyper stimulation syndrome (OHSS) and high order multiple pregnancies.
Egg Retrieval is a vital process in IVF. To understand how this is performed at the Raipur Fertility centre, we need to go through the following steps:
o Ultrasound- guided Trans-vaginal Aspiration
Preparation: IVF begins with ovulation induction which is the process of stimulating and inducting the ovaries. Once the eggs are ready to be collected, a dose of HCG (human chorionic) is given to trigger the process and after 36 hours egg retrieval is done. Prior to the procedure, anaesthesia is given. In most cases, patient will sleep through this procedure.
Ultrasound- guided Trans-vaginal Aspiration: This is the egg collection procedure. Here a visual image of the ovary along with its surrounding is created with the help of an ultrasound probe. Using a fine needle, trough the upper wall of the vagina and into the ovary the insertion is done. The ultra sound image is magnified which helps the physician to locate the individual follicles which contain the mature eggs. With gentle suction the contents are removed and this is referred to as aspiration.
At Raipur Fertility Centre this is done under general anesthesia as it is safe and gentle for the patients and allows the doctors to collect more eggs.
Using a container the egg and fluid from each follicle are collected for examination and further preparation. The procedure is very precise, requires considerable skill and is performed on both ovaries. It takes around 15-30 minutes to complete depending upon the number of eggs. Once the egg retrieval process is completed, the patient is kept under observation for one or two hours and discharged.
Recovery: It is observed that post egg retrieval there are some minor discomfort like cramping, soreness and light spotting. Hence proper rest is required with restrictions on physical activities as advised.
Progesterone is a very critical hormone for supporting the early pregnancy and is normally released by the follicle after evolution. The normal hormonal process is often disturbed by the aspiration of the follicles and hence the required amount of progesterone may not be produced. In these cases the patient is required to be administered supplemental progesterone which starts from egg retrieval and is continued till the end of the cycle.
At this stage, the sperm and eggs finally come together. Literally meaning “fertilization in glass” the fertility experts at Raipur Centre, India are able to help patients overcome numerus type of fertility problems. The following need to be clarified for a proper understanding of the procedure that takes place at this stage:
o Insemination and Fertilization
o Embryo Development
o Embryo Co-Culture
Preparation: After ovulation induction and egg retrieval, the collected eggs are examined and prepared for IVF. Semen collection is done on the same day as the egg retrieval procedure and is examined properly. Washing and sorting of the sperms is done so that only the best sperm are combined with the eggs to maximise the chances of successful fertilization.
Insemination and Fertilization: Post the preparation of the sperms and the eggs; they are combined in a dish with a special IVF culture. This helps in giving the required nourishment to develop. Each dish is placed inside the incubator while the IVF takes place. After 18 hours the dishes are retrieved for examination. Successfully fertilized eggs are identified at this stage and kept again in the incubator. The ones which are still unfertilized post the 18 hours are over are the ones which need to be discarded as they will not be fertilized now.
Embryo Development: Once fertilization takes place, cell division begins. At this stage the embryos will continue to be observed at regular intervals until at least 3 days post IVF. Rate of growth will be monitored with close watch on any abnormalities. Certain factors and norms are required and the same are vital for embryo to be transferred. Embryos which are multi nuclear or don’t develop cannot be transferred and will be discarded.
After three days of development the embryo transfer is done.
Embryo Co- Culture: In most cases of IVF, the embryos are formed and developed in a culture medium which is developed in a laboratory especially for IVF. To support the developing embryo, a sample of endometrium cells can also be used. For some women this increases the chance of successful implantation after embryo transfer.
This is the final stage of IVF. Here post the creation of the embryos they need to be placed in the uterus. This two week wait which is required post the embryo transfer and the initial pregnancy test can be very difficult and anxious for most patients. The qualified and dedicated team at the Raipur centre believes that understanding IVF and all its components is the key to coping with the stress that accompanies the treatment.
o Embryo Selection
o Embryo Transfer
o Recovery & Implantation
o What’s Next
Embryo Selection: During the development stage, the embryos are monitored for their growth rate, size, formation and other factors. Basis the above findings, the embryos are judged to analyse the best quality for successful implantation. The best quality is selected for embryo transfer. Embryos with significant abnormalities are not suitable for transfer and discarded.
Embryo Transfer: This procedure of embryo transfer in IVF Raipur is usually done around three to five days after the egg retrieval is done. There would be certain IVF cycles where frozen embryos are used. In such cases, ultrasound examination is done and patient is monitored well. After two days of ovulation, the embryos will be placed. A thin catheter is threaded through the opening in the cervix and the embryos are gently deposited into the uterus. There is very little discomfort in this procedure and anaesthesia is not required.
Recovery & Implantation: After the transfer procedure, the patients are advised to take it easy for next few days. It is advisable to have limited physical activity with complete restriction on strenuous activities. While nothing much can be done at this point which will help in successful implantation, a proper diet and rest with minimum stress will go a long way towards the health and well being of the patient.
Testing: After approximately fourteen days post the embryo transfer procedure, a blood test is done which will measure the amount of HCG or human chorionic gonadotropin. This is required as this hormone is released only post implantation and hence will help in detecting pregnancy. If the pregnancy is detected an ultrasound scan is done for confirmation and determination of the number of embryos implanted and ensures a normal progress.
What’s next? : If pregnancy has taken place, progesterone treatments will be continued for a period of time and then be gradually reduced as gradually the body will take charge of the normal hormone production. Also a regular OB- GYN will now be required for the complete prenatal care. In case pregnancy has not taken place, progesterone supplements are stopped and cycle is ended. If the couple wants to go for another IVF cycle, it is advisable to wait for one or maybe two complete menstrual cycles and then start fresh treatment. This allows the body time to recover and is also a time for us at the Raipur centre a chance to review our treatment in details and if required do some strategy changes in the forthcoming cycles. Also if the frozen embryos are available for transfer, the ovulation induction phase will not be required in the subsequent IVF cycles.
IVF Risks & Complications
Many couples are worried that babies born after IVF are abnormal or weak. At the outset we need to keep in mind that there is nothing artificial about these babies. They are not synthetic babies being manufactured in the laboratory. IVF is a form of assisted reproductive technology where technology assists nature to do what could not be done in a natural manner. Over a hundred thousand babies have been born after IVF treatment however birth defects have not gone up.
Ovarian hyper stimulation syndrome (OHSS) due to super ovulation is a critical complication which can happen due to IVF. However this can be treated properly at the Raipur Fertility clinic.
In all the methods associated with assisted reproductive technology, the chances of multiple pregnancies are considerably higher. This happens as more than one egg or embryo is transferred. Once again there are solutions and treatments for multiple pregnancies. Also there is very minute chance of an ectopic pregnancy with IVF. However this is not due to the procedure but it happens due to the fact that women going through IVF already have damaged tubes which make them vulnerable to having an ectopic.
Success Rate of IVF at Raipur Fertility Centre Chhattisgarh, India
The pregnancy rates at Raipur Fertility Centre are one of the best pregnancy rates per embryo transfer. This high rate of pregnancy per embryo transfer is important as it reduces the overall cost of treatment. It also helps in minimizing the discomfort, saves time which is required for multiple egg retrievals.
Couples considering IVF can best evaluate and compare the IVF clinics once they look at the success rate.
Raipur Fertility Centre is providing world class treatment and our excellence can be measured with our success rate. With a mission of helping couples to create dreams, you will get low cost IVF with the best technology and team in Chhattisgarh.
International Patients can call or Whats App Mr Bryaen Connor on 0091 9873083334